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Identification of POMC Exonic Variants Associated with Substance Dependence and Body Mass Index

BACKGROUND: Risk of substance dependence (SD) and obesity has been linked to the function of melanocortin peptides encoded by the proopiomelanocortin gene (POMC). METHODS AND RESULTS: POMC exons were Sanger sequenced in 280 African Americans (AAs) and 308 European Americans (EAs). Among them, 311 (1...

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Detalles Bibliográficos
Autores principales: Wang, Fan, Gelernter, Joel, Kranzler, Henry R., Zhang, Huiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444488/
https://www.ncbi.nlm.nih.gov/pubmed/23028917
http://dx.doi.org/10.1371/journal.pone.0045300