Activation-Induced Cytidine Deaminase Alters the Subcellular Localization of Tet Family Proteins

Activation-induced cytidine deminase (Aid), a unique enzyme that deaminates cytosine in DNA, shuttles between the nucleus and the cytoplasm. A recent study proposed a novel function of Aid in active DNA demethylation via deamination of 5-hydroxymethylcytosine, which is converted from 5-methylcytosin...

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Detalles Bibliográficos
Autores principales: Arioka, Yuko, Watanabe, Akira, Saito, Kuniaki, Yamada, Yasuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444495/
https://www.ncbi.nlm.nih.gov/pubmed/23028748
http://dx.doi.org/10.1371/journal.pone.0045031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444495/
https://www.ncbi.nlm.nih.gov/pubmed/23028748
http://dx.doi.org/10.1371/journal.pone.0045031

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