Sirenomelia Phenotype in Bmp7;Shh Compound Mutants: A Novel Experimental Model for Studies of Caudal Body Malformations

Sirenomelia is a severe congenital malformation of the lower body characterized by the fusion of the legs into a single lower limb. This striking external phenotype consistently associates severe visceral abnormalities, most commonly of the kidneys, intestine, and genitalia that generally make the c...

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Detalles Bibliográficos
Autores principales: Garrido-Allepuz, Carlos, González-Lamuño, Domingo, Ros, Maria A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444499/
https://www.ncbi.nlm.nih.gov/pubmed/23028704
http://dx.doi.org/10.1371/journal.pone.0044962

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444499/
https://www.ncbi.nlm.nih.gov/pubmed/23028704
http://dx.doi.org/10.1371/journal.pone.0044962

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