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Molecular and pharmacological evidence for a facilitatory functional role of pre-synaptic GLUK2/3 kainate receptors on GABA release in rat trigeminal caudal nucleus

BACKGROUND: Gamma-aminobutyric acid (GABA) and glutamate (GLU) are involved in nociceptive signals processing in the trigeminal system. In this study, we investigated the influence of excitatory transmission on GABA release in nerve terminals isolated from the rat trigeminal caudal nucleus (TCN). ME...

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Detalles Bibliográficos
Autores principales: Samengo, I, Currò, D, Navarra, P, Barrese, V, Taglialatela, M, Martire, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444694/
https://www.ncbi.nlm.nih.gov/pubmed/22392917
http://dx.doi.org/10.1002/j.1532-2149.2012.00122.x