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Intracerebral immune complex formation induces inflammation in the brain that depends on Fc receptor interaction

In this study, we investigate the underlying mechanisms of antibody-mediated inflammation in the brain. We show that immune complexes formed in the brain parenchyma generate a robust and long-lasting inflammatory response, characterized by increased expression of the microglia markers CD11b, CD68 an...

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Detalles Bibliográficos
Autores principales: Teeling, Jessica L., Carare, Roxana O., Glennie, Martin J., Perry, V. Hugh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444701/
https://www.ncbi.nlm.nih.gov/pubmed/22618994
http://dx.doi.org/10.1007/s00401-012-0995-3