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Intracerebral immune complex formation induces inflammation in the brain that depends on Fc receptor interaction
In this study, we investigate the underlying mechanisms of antibody-mediated inflammation in the brain. We show that immune complexes formed in the brain parenchyma generate a robust and long-lasting inflammatory response, characterized by increased expression of the microglia markers CD11b, CD68 an...
Autores principales: | Teeling, Jessica L., Carare, Roxana O., Glennie, Martin J., Perry, V. Hugh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444701/ https://www.ncbi.nlm.nih.gov/pubmed/22618994 http://dx.doi.org/10.1007/s00401-012-0995-3 |
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