Heparanase overexpression impairs inflammatory response and macrophage-mediated clearance of amyloid-β in murine brain

Neuroinflammation is typically observed in neurodegenerative diseases such as Alzheimer’s disease, as well as after traumatic injury and pathogen infection. Resident immune cells, microglia and astrocytes, are activated and joined by blood-borne monocytes that traverse the blood–brain barrier and co...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Xiao, Wang, Bo, O’Callaghan, Paul, Hjertström, Elina, Jia, Juan, Gong, Feng, Zcharia, Eyal, Nilsson, Lars N. G., Lannfelt, Lars, Vlodavsky, Israel, Lindahl, Ulf, Li, Jin-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444710/
https://www.ncbi.nlm.nih.gov/pubmed/22692572
http://dx.doi.org/10.1007/s00401-012-0997-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444710/
https://www.ncbi.nlm.nih.gov/pubmed/22692572
http://dx.doi.org/10.1007/s00401-012-0997-1

Ejemplares similares