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Heparanase overexpression impairs inflammatory response and macrophage-mediated clearance of amyloid-β in murine brain
Neuroinflammation is typically observed in neurodegenerative diseases such as Alzheimer’s disease, as well as after traumatic injury and pathogen infection. Resident immune cells, microglia and astrocytes, are activated and joined by blood-borne monocytes that traverse the blood–brain barrier and co...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer-Verlag
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444710/ https://www.ncbi.nlm.nih.gov/pubmed/22692572 http://dx.doi.org/10.1007/s00401-012-0997-1 |