NLRP3-Inflammasome Activating DAMPs Stimulate an Inflammatory Response in Glia in the Absence of Priming Which Contributes to Brain Inflammation after Injury

Inflammation in the absence of infection (sterile inflammation) contributes to acute injury and chronic disease. Cerebral ischemia is a devastating condition in which the primary injury is caused by reduced blood supply and is therefore sterile. The cytokine interleukin-1β (IL-1β) is a key contribut...

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Detalles Bibliográficos
Autores principales: Savage, Catherine Diane, Lopez-Castejon, Gloria, Denes, Adam, Brough, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444764/
https://www.ncbi.nlm.nih.gov/pubmed/23024646
http://dx.doi.org/10.3389/fimmu.2012.00288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444764/
https://www.ncbi.nlm.nih.gov/pubmed/23024646
http://dx.doi.org/10.3389/fimmu.2012.00288

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