PDE5 Inhibitors as Potential Tools in the Treatment of Cystic Fibrosis

Despite great advances in the understanding of the genetics and pathophysiology of cystic fibrosis (CF), there is still no cure for the disease. Using phosphodiesterase type 5 (PDE5) inhibitors, we and others have provided evidence of rescued F508del-CFTR trafficking and corrected deficient chloride...

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Detalles Bibliográficos
Autores principales: Noel, Sabrina, Dhooghe, Barbara, Leal, Teresinha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444771/
https://www.ncbi.nlm.nih.gov/pubmed/23024633
http://dx.doi.org/10.3389/fphar.2012.00167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444771/
https://www.ncbi.nlm.nih.gov/pubmed/23024633
http://dx.doi.org/10.3389/fphar.2012.00167

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