Crumbs limits oxidase-dependent signaling to maintain epithelial integrity and prevent photoreceptor cell death

Drosophila melanogaster Crumbs (Crb) and its mammalian orthologues (CRB1–3) share evolutionarily conserved but poorly defined roles in regulating epithelial polarity and, in photoreceptor cells, morphogenesis and stability. Elucidating the molecular mechanisms of Crb function is vital, as mutations...

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Detalles Bibliográficos
Autores principales: Chartier, François J.-M., Hardy, Émilie J.-L., Laprise, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444775/
https://www.ncbi.nlm.nih.gov/pubmed/22965909
http://dx.doi.org/10.1083/jcb.201203083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444775/
https://www.ncbi.nlm.nih.gov/pubmed/22965909
http://dx.doi.org/10.1083/jcb.201203083

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