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Crumbs limits oxidase-dependent signaling to maintain epithelial integrity and prevent photoreceptor cell death
Drosophila melanogaster Crumbs (Crb) and its mammalian orthologues (CRB1–3) share evolutionarily conserved but poorly defined roles in regulating epithelial polarity and, in photoreceptor cells, morphogenesis and stability. Elucidating the molecular mechanisms of Crb function is vital, as mutations...
Autores principales: | Chartier, François J.-M., Hardy, Émilie J.-L., Laprise, Patrick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444775/ https://www.ncbi.nlm.nih.gov/pubmed/22965909 http://dx.doi.org/10.1083/jcb.201203083 |
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