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Dynein light chain 1 and a spindle-associated adaptor promote dynein asymmetry and spindle orientation

The cytoplasmic dynein motor generates pulling forces to center and orient the mitotic spindle within the cell. During this positioning process, dynein oscillates from one pole of the cell cortex to the other but only accumulates at the pole farthest from the spindle. Here, we show that dynein light...

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Detalles Bibliográficos
Autores principales: Dunsch, Anja K., Hammond, Dean, Lloyd, Jennifer, Schermelleh, Lothar, Gruneberg, Ulrike, Barr, Francis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444778/
https://www.ncbi.nlm.nih.gov/pubmed/22965910
http://dx.doi.org/10.1083/jcb.201202112