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Mast Cell Leukaemia: c-KIT Mutations Are Not Always Positive

Mast cell leukemia (MCL) is a rare and aggressive disease with poor prognosis and short survival time. D816V c-KIT mutation is the most frequent molecular abnormality and plays a crucial role in the pathogenesis and development of the disease. Thus, comprehensive diagnostic investigations and molecu...

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Detalles Bibliográficos
Autores principales: Joris, Magalie, Georgin-Lavialle, Sophie, Chandesris, Marie-Olivia, Lhermitte, Ludovic, Claisse, Jean-François, Canioni, Danielle, Hanssens, Katia, Damaj, Gandhi, Hermine, Olivier, Hamidou, Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444844/
https://www.ncbi.nlm.nih.gov/pubmed/22997594
http://dx.doi.org/10.1155/2012/517546