TGFβ1 Controls PPARγ Expression, Transcriptional Potential, and Activity, in Part, through Smad3 Signaling in Murine Lung Fibroblasts

Transforming growth factor β1 (TGFβ1) promotes fibrosis by, among other mechanisms, activating quiescent fibroblasts into myofibroblasts and increasing the expression of extracellular matrices. Recent work suggests that peroxisome proliferator-activated receptor γ (PPARγ) is a negative regulator of...

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Detalles Bibliográficos
Autores principales: Ramirez, Allan, Ballard, Erin N., Roman, Jesse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444904/
https://www.ncbi.nlm.nih.gov/pubmed/22997505
http://dx.doi.org/10.1155/2012/375876

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444904/
https://www.ncbi.nlm.nih.gov/pubmed/22997505
http://dx.doi.org/10.1155/2012/375876

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