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A shot in the genome: how accurately do shotgun 454 sequences represent a genome?
BACKGROUND: Next generation sequencing (NGS) provides a valuable method to quickly obtain sequence information from non-model organisms at a genomic scale. In principle, if sequencing is not targeted for a genomic region or sequence type (e.g. coding region, microsatellites) NGS reads can be used as...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444912/ https://www.ncbi.nlm.nih.gov/pubmed/22640415 http://dx.doi.org/10.1186/1756-0500-5-259 |