Cytotoxicity of 15-Deoxy-Δ(12,14)-prostaglandin J(2) through PPARγ-independent Pathway and the Involvement of the JNK and Akt Pathway in Renal Cell Carcinoma

Introduction: Agonists of peroxisome proliferator-activated receptor gamma (PPARγ) have been examined as chemopreventive and chemotherapeutic agents. The aim was to investigate the cytotoxicity and action mechanisms of 15-deoxy-Δ(12,14)-prostaglandin J(2) (15d-PGJ(2)), one of endogenous ligands for...

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Detalles Bibliográficos
Autores principales: Fujita, Megumi, Tohji, Chiaki, Honda, Yoko, Yamamoto, Yasuhiro, Nakamura, Tsutomu, Yagami, Tatsurou, Yamamori, Motohiro, Okamura, Noboru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2012
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444976/
https://www.ncbi.nlm.nih.gov/pubmed/22991494
http://dx.doi.org/10.7150/ijms.4455

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444976/
https://www.ncbi.nlm.nih.gov/pubmed/22991494
http://dx.doi.org/10.7150/ijms.4455

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