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Structural and Functional Analysis of the NLRP4 Pyrin Domain

[Image: see text] NLRP4 is a member of the nucleotide-binding and leucine-rich repeat receptor (NLR) family of cytosolic receptors and a member of an inflammation signaling cascade. Here, we present the crystal structure of the NLRP4 pyrin domain (PYD) at 2.3 Å resolution. The NLRP4 PYD is a member...

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Detalles Bibliográficos
Autores principales: Eibl, Clarissa, Grigoriu, Simina, Hessenberger, Manuel, Wenger, Julia, Puehringer, Sandra, Pinheiro, Anderson S., Wagner, Roland N., Proell, Martina, Reed, John C., Page, Rebecca, Diederichs, Kay, Peti, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2012
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445046/
https://www.ncbi.nlm.nih.gov/pubmed/22928810
http://dx.doi.org/10.1021/bi3007059