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The Role of Magnesium Supplementation in Cisplatin-induced Nephrotoxicity in a Rat Model: No Nephroprotectant Effect

OBJECTIVES: Cisplatin (CP) is used as the commonest drug to treat solid tumors. It is accompanied by a nephrotoxicity side effect. The main objective of this study is to investigate the protective role of magnesium (Mg) supplementation in CP-induced nephrotoxicity in a rat model. METHODS: Twenty-nin...

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Detalles Bibliográficos
Autores principales: Ashrafi, Farzaneh, Haghshenas, Sara, Nematbakhsh, Mehdi, Nasri, Hamid, Talebi, Ardeshir, Eshraghi-Jazi, Fatemeh, Pezeshki, Zahra, Safari, Tahereh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445280/
https://www.ncbi.nlm.nih.gov/pubmed/23024853