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TRC40 can deliver short secretory proteins to the Sec61 translocon

Whilst the co-translational translocation of nascent proteins across the mammalian endoplasmic reticulum (ER) is well defined, the capacity of this organelle for post-translational translocation is poorly delineated. Here we identify two human secretory protein precursors, apelin and statherin, as b...

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Detalles Bibliográficos
Autores principales: Johnson, Nicholas, Vilardi, Fabio, Lang, Sven, Leznicki, Pawel, Zimmermann, Richard, High, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445324/
https://www.ncbi.nlm.nih.gov/pubmed/22505607
http://dx.doi.org/10.1242/jcs.102608