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SUMOylation of HNF4α regulates protein stability and hepatocyte function

The coordination of signalling pathways within the cell is vital for normal human development and post-natal tissue homeostasis. Gene expression and function is therefore tightly controlled at a number of levels. We investigated the role that post-translational modifications play during human hepato...

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Detalles Bibliográficos
Autores principales: Zhou, Wenli, Hannoun, Zara, Jaffray, Ellis, Medine, Claire N., Black, James R., Greenhough, Sebastian, Zhu, Liang, Ross, James A., Forbes, Stuart, Wilmut, Ian, Iredale, John P., Hay, Ronald T., Hay, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445325/
https://www.ncbi.nlm.nih.gov/pubmed/22505616
http://dx.doi.org/10.1242/jcs.102889