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Inhibition of Bacterial Virulence: Drug-Like Molecules Targeting the Salmonella enterica PhoP Response Regulator

Two-component signal transduction (TCST) is the predominant signaling scheme used in bacteria to sense and respond to environmental changes in order to survive and thrive. A typical TCST system consists of a sensor histidine kinase to detect external signals and an effector response regulator to res...

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Detalles Bibliográficos
Autores principales: Tang, Yat T, Gao, Rong, Havranek, James J, Groisman, Eduardo A, Stock, Ann M, Marshall, Garland R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445336/
https://www.ncbi.nlm.nih.gov/pubmed/22339993
http://dx.doi.org/10.1111/j.1747-0285.2012.01362.x