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SIRT1 Regulates Endothelial Notch Signaling in Lung Cancer

BACKGROUND: Sirtuin 1 (SIRT1) acts as a key regulator of vascular endothelial homeostasis, angiogenesis, and endothelial dysfunction. However, the underlying mechanism for SIRT1-mediated lung carcinoma angiogenesis remains unknown. Herein, we report that the nicotinamide adenine dinucleotide 1 (NAD1...

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Detalles Bibliográficos
Autores principales: Xie, Mian, Liu, Ming, He, Chao-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445453/
https://www.ncbi.nlm.nih.gov/pubmed/23028940
http://dx.doi.org/10.1371/journal.pone.0045331