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Rescue the Failed Half-ZFN by a Sensitive Mammalian Cell-Based Luciferase Reporter System
ZFN technology is a powerful research tool and has been used for genome editing in cells lines, animals and plants. The generation of functional ZFNs for particular targets in mammalian genome is still challenging for an average research group. The modular-assembly method is relatively fast, easy-to...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445457/ https://www.ncbi.nlm.nih.gov/pubmed/23028823 http://dx.doi.org/10.1371/journal.pone.0045169 |