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Rescue the Failed Half-ZFN by a Sensitive Mammalian Cell-Based Luciferase Reporter System

ZFN technology is a powerful research tool and has been used for genome editing in cells lines, animals and plants. The generation of functional ZFNs for particular targets in mammalian genome is still challenging for an average research group. The modular-assembly method is relatively fast, easy-to...

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Detalles Bibliográficos
Autores principales: Zhang, Weifeng, Guo, Yuanxu, Zhang, Chen, Ji, Haiyan, Meng, Wenpeng, Wang, Dongyang, Li, Xing, Mao, Qinwen, Xia, Haibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445457/
https://www.ncbi.nlm.nih.gov/pubmed/23028823
http://dx.doi.org/10.1371/journal.pone.0045169