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Differential Gene and MicroRNA Expression between Etoposide Resistant and Etoposide Sensitive MCF7 Breast Cancer Cell Lines

In order to develop targeted strategies for combating drug resistance it is essential to understand it’s basic molecular mechanisms. In an exploratory study we have found several possible indicators of etoposide resistance operating in MCF7VP cells, including up-regulation of ABC transporter genes,...

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Detalles Bibliográficos
Autores principales: Moitra, Karobi, Im, Kate, Limpert, Katy, Borsa, Alexander, Sawitzke, Julie, Robey, Rob, Yuhki, Naoya, Savan, Ram, Huang, Da Wei, Lempicki, Richard A., Bates, Susan, Dean, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445463/
https://www.ncbi.nlm.nih.gov/pubmed/23028896
http://dx.doi.org/10.1371/journal.pone.0045268