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Characterization of In Vivo Dlg1 Deletion on T Cell Development and Function

BACKGROUND: The polarized reorganization of the T cell membrane and intracellular signaling molecules in response to T cell receptor (TCR) engagement has been implicated in the modulation of T cell development and effector responses. In siRNA-based studies Dlg1, a MAGUK scaffold protein and member o...

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Detalles Bibliográficos
Autores principales: Humphries, Lisa A., Shaffer, Meredith H., Sacirbegovic, Faruk, Tomassian, Tamar, McMahon, Kerrie-Ann, Humbert, Patrick O., Silva, Oscar, Round, June L., Takamiya, Kogo, Huganir, Richard L., Burkhardt, Janis K., Russell, Sarah M., Miceli, M. Carrie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445470/
https://www.ncbi.nlm.nih.gov/pubmed/23028902
http://dx.doi.org/10.1371/journal.pone.0045276