Idebenone Protects against Retinal Damage and Loss of Vision in a Mouse Model of Leber’s Hereditary Optic Neuropathy

Leber’s hereditary optic neuropathy (LHON) is an inherited disease caused by mutations in complex I of the mitochondrial respiratory chain. The disease is characterized by loss of central vision due to retinal ganglion cell (RGC) dysfunction and optic nerve atrophy. Despite progress towards a better...

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Detalles Bibliográficos
Autores principales: Heitz, Fabrice D., Erb, Michael, Anklin, Corinne, Robay, Dimitri, Pernet, Vincent, Gueven, Nuri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445472/
https://www.ncbi.nlm.nih.gov/pubmed/23028832
http://dx.doi.org/10.1371/journal.pone.0045182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445472/
https://www.ncbi.nlm.nih.gov/pubmed/23028832
http://dx.doi.org/10.1371/journal.pone.0045182

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