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Idebenone Protects against Retinal Damage and Loss of Vision in a Mouse Model of Leber’s Hereditary Optic Neuropathy
Leber’s hereditary optic neuropathy (LHON) is an inherited disease caused by mutations in complex I of the mitochondrial respiratory chain. The disease is characterized by loss of central vision due to retinal ganglion cell (RGC) dysfunction and optic nerve atrophy. Despite progress towards a better...
Autores principales: | Heitz, Fabrice D., Erb, Michael, Anklin, Corinne, Robay, Dimitri, Pernet, Vincent, Gueven, Nuri |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445472/ https://www.ncbi.nlm.nih.gov/pubmed/23028832 http://dx.doi.org/10.1371/journal.pone.0045182 |
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