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HuR Is Necessary for Mammary Epithelial Cell Proliferation and Polarity at Least in Part via ΔNp63

HuR, a RNA binding protein, is known to function as a tumor maintenance gene in breast cancer and associated with tumor growth and poor prognosis. However, the cellular function of this protein remains largely unknown in normal mammary epithelial cells. Here, we showed that in immortalized MCF10A ma...

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Detalles Bibliográficos
Autores principales: Yan, Wensheng, Zhang, Yanhong, Zhang, Jin, Cho, Seong-Jun, Chen, Xinbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445479/
https://www.ncbi.nlm.nih.gov/pubmed/23028944
http://dx.doi.org/10.1371/journal.pone.0045336