A Targeted Library Screen Reveals a New Inhibitor Scaffold for Protein Kinase D

Protein kinase D (PKD) has emerged as a potential therapeutic target in multiple pathological conditions, including cancer and heart diseases. Potent and selective small molecule inhibitors of PKD are valuable for dissecting PKD-mediated cellular signaling pathways and for therapeutic application. I...

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Detalles Bibliográficos
Autores principales: Tandon, Manuj, Wang, Lirong, Xu, Qi, Xie, Xiangqun, Wipf, Peter, Wang, Qiming Jane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445516/
https://www.ncbi.nlm.nih.gov/pubmed/23028574
http://dx.doi.org/10.1371/journal.pone.0044653

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445516/
https://www.ncbi.nlm.nih.gov/pubmed/23028574
http://dx.doi.org/10.1371/journal.pone.0044653

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