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Heterodimeric Barnase-Barstar Vaccine Molecules: Influence of One versus Two Targeting Units Specific for Antigen Presenting Cells

It is known that targeting of antigen to antigen presenting cells (APC) increases immune responses. However, it is unclear if more than one APC-specific targeting unit in the antigenic molecule will increase responses. To address this issue, we have here made heterodimeric vaccine molecules that eac...

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Detalles Bibliográficos
Autores principales: Spång, Heidi Cecilie Larsen, Braathen, Ranveig, Bogen, Bjarne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445521/
https://www.ncbi.nlm.nih.gov/pubmed/23028981
http://dx.doi.org/10.1371/journal.pone.0045393