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Dynamical Behaviors of Rb-E2F Pathway Including Negative Feedback Loops Involving miR449

MiRNAs, which are a family of small non-coding RNAs, regulate a broad array of physiological and developmental processes. However, their regulatory roles have remained largely mysterious. E2F is a positive regulator of cell cycle progression and also a potent inducer of apoptosis. Positive feedback...

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Detalles Bibliográficos
Autores principales: Yan, Fang, Liu, Haihong, Hao, Junjun, Liu, Zengrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445561/
https://www.ncbi.nlm.nih.gov/pubmed/23028477
http://dx.doi.org/10.1371/journal.pone.0043908