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Dynamical Behaviors of Rb-E2F Pathway Including Negative Feedback Loops Involving miR449
MiRNAs, which are a family of small non-coding RNAs, regulate a broad array of physiological and developmental processes. However, their regulatory roles have remained largely mysterious. E2F is a positive regulator of cell cycle progression and also a potent inducer of apoptosis. Positive feedback...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445561/ https://www.ncbi.nlm.nih.gov/pubmed/23028477 http://dx.doi.org/10.1371/journal.pone.0043908 |