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Zinc Finger Binding Motifs Do Not Explain Recombination Rate Variation within or between Species of Drosophila
In humans and mice, the Cys(2)His(2) zinc finger protein PRDM9 binds to a DNA sequence motif enriched in hotspots of recombination, possibly modifying nucleosomes, and recruiting recombination machinery to initiate Double Strand Breaks (DSBs). However, since its discovery, some researchers have sugg...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445564/ https://www.ncbi.nlm.nih.gov/pubmed/23028758 http://dx.doi.org/10.1371/journal.pone.0045055 |