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The Aspergillus fumigatus Dihydroxyacid Dehydratase Ilv3A/IlvC Is Required for Full Virulence

Dihydroxyacid dehydratase (DHAD) is a key enzyme in the branched-chain amino acid biosynthetic pathway that exists in a variety of organisms, including fungi, plants and bacteria, but not humans. In this study we identified four putative DHAD genes from the filamentous fungus Aspergillus fumigatus b...

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Detalles Bibliográficos
Autores principales: Oliver, Jason D., Kaye, Sarah J., Tuckwell, Danny, Johns, Anna E., Macdonald, Darel A., Livermore, Joanne, Warn, Peter A., Birch, Mike, Bromley, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445565/
https://www.ncbi.nlm.nih.gov/pubmed/23028460
http://dx.doi.org/10.1371/journal.pone.0043559