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The Insect Pathogen Serratia marcescens Db10 Uses a Hybrid Non-Ribosomal Peptide Synthetase-Polyketide Synthase to Produce the Antibiotic Althiomycin

There is a continuing need to discover new bioactive natural products, such as antibiotics, in genetically-amenable micro-organisms. We observed that the enteric insect pathogen, Serratia marcescens Db10, produced a diffusible compound that inhibited the growth of Bacillis subtilis and Staphyloccocu...

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Detalles Bibliográficos
Autores principales: Gerc, Amy J., Song, Lijiang, Challis, Gregory L., Stanley-Wall, Nicola R., Coulthurst, Sarah J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445576/
https://www.ncbi.nlm.nih.gov/pubmed/23028578
http://dx.doi.org/10.1371/journal.pone.0044673