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Transcriptional Differences between Rhesus Embryonic Stem Cells Generated from In Vitro and In Vivo Derived Embryos

Numerous studies have focused on the transcriptional signatures that underlie the maintenance of embryonic stem cell (ESC) pluripotency. However, it remains unclear whether ESC retain transcriptional aberrations seen in in vitro cultured embryos. Here we report the first global transcriptional profi...

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Detalles Bibliográficos
Autores principales: Harvey, Alexandra J., Mao, Shihong, Lalancette, Claudia, Krawetz, Stephen A., Brenner, Carol A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445581/
https://www.ncbi.nlm.nih.gov/pubmed/23028448
http://dx.doi.org/10.1371/journal.pone.0043239