NEMO Binds Ubiquitinated TANK-Binding Kinase 1 (TBK1) to Regulate Innate Immune Responses to RNA Viruses

RIG-I-like receptors (RLR) are intracellular sensors utilized by nearly all cell types for recognition of viral RNA, initiation of antiviral defense, and induction of type I interferons (IFN). TBK1 is a critical kinase implicated in RLR-dependent IFN transcription. Posttranslational modification of...

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Detalles Bibliográficos
Autores principales: Wang, Lingyan, Li, Shitao, Dorf, Martin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445589/
https://www.ncbi.nlm.nih.gov/pubmed/23028469
http://dx.doi.org/10.1371/journal.pone.0043756

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445589/
https://www.ncbi.nlm.nih.gov/pubmed/23028469
http://dx.doi.org/10.1371/journal.pone.0043756

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