Model Hirano Bodies Protect against Tau-Independent and Tau-Dependent Cell Death Initiated by the Amyloid Precursor Protein Intracellular Domain

The main pathological hallmarks of Alzheimer’s disease are amyloid-beta plaques and neurofibrillary tangles, which are primarily composed of amyloid precursor protein (APP) and tau, respectively. These proteins and their role in the mechanism of neurodegeneration have been extensively studied. Hiran...

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Detalles Bibliográficos
Autores principales: Furgerson, Matthew, Fechheimer, Marcus, Furukawa, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445605/
https://www.ncbi.nlm.nih.gov/pubmed/23028730
http://dx.doi.org/10.1371/journal.pone.0044996

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445605/
https://www.ncbi.nlm.nih.gov/pubmed/23028730
http://dx.doi.org/10.1371/journal.pone.0044996

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