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Requirement of PML SUMO Interacting Motif for RNF4- or Arsenic Trioxide-Induced Degradation of Nuclear PML Isoforms

PML, the organizer of nuclear bodies (NBs), is expressed in several isoforms designated PMLI to VII which differ in their C-terminal region due to alternative splicing of a single gene. This variability is important for the function of the different PML isoforms. PML NB formation requires the covale...

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Detalles Bibliográficos
Autores principales: Maroui, Mohamed Ali, Kheddache-Atmane, Sabrina, El Asmi, Faten, Dianoux, Laurent, Aubry, Muriel, Chelbi-Alix, Mounira K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445614/
https://www.ncbi.nlm.nih.gov/pubmed/23028697
http://dx.doi.org/10.1371/journal.pone.0044949