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Pluripotent stem cells reveal the developmental biology of human megakaryocytes and provide a source of platelets for clinical application
Human pluripotent stem cells [PSCs; including human embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs)] can infinitely proliferate in vitro and are easily accessible for gene manipulation. Megakaryocytes (MKs) and platelets can be created from human ESCs and iPSCs in vitro and re...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SP Birkhäuser Verlag Basel
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445798/ https://www.ncbi.nlm.nih.gov/pubmed/22527724 http://dx.doi.org/10.1007/s00018-012-0995-4 |