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Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)

Many components and pathways transducing multifaceted and deleterious effects of stress stimuli remain ill-defined. The Ran-binding protein 2 (RanBP2) interactome modulates the expression of a range of clinical and cell-context-dependent manifestations upon a variety of stressors. We examined the ro...

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Detalles Bibliográficos
Autores principales: Cho, Kyoung-in, Searle, Kelly, Webb, Mason, Yi, Haiqing, Ferreira, Paulo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SP Birkhäuser Verlag Basel 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445802/
https://www.ncbi.nlm.nih.gov/pubmed/22821000
http://dx.doi.org/10.1007/s00018-012-1071-9