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Differential effects of simvastatin on IL-13-induced cytokine gene expression in primary mouse tracheal epithelial cells
BACKGROUND: Asthma causes significant morbidity worldwide in adults and children alike, and incurs large healthcare costs. The statin drugs, which treat hyperlipidemia and cardiovascular diseases, have pleiotropic effects beyond lowering cholesterol, including immunomodulatory, anti-inflammatory, an...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445818/ https://www.ncbi.nlm.nih.gov/pubmed/22583375 http://dx.doi.org/10.1186/1465-9921-13-38 |