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What inference for two-stage phase II trials?

BACKGROUND: Simon’s two-stage designs are widely used for cancer phase II trials. These methods rely on statistical testing and thus allow controlling the type I and II error rates, while accounting for the interim analysis. Estimation after such trials is however not straightforward, and several di...

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Detalles Bibliográficos
Autores principales: Porcher, Raphaël, Desseaux, Kristell
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445829/
https://www.ncbi.nlm.nih.gov/pubmed/22867439
http://dx.doi.org/10.1186/1471-2288-12-117

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