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Leishmania promastigotes: building a safe niche within macrophages

Upon their internalization by macrophages, Leishmania promastigotes inhibit phagolysosome biogenesis. The main factor responsible for this inhibition is the promastigote surface glycolipid lipophosphoglycan (LPG). This glycolipid has a profound impact on the phagosome, causing periphagosomal accumul...

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Detalles Bibliográficos
Autores principales: Moradin, Neda, Descoteaux, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445913/
https://www.ncbi.nlm.nih.gov/pubmed/23050244
http://dx.doi.org/10.3389/fcimb.2012.00121