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Chronic Treatment With Aripiprazole Prevents Development of Dopamine Supersensitivity and Potentially Supersensitivity Psychosis

Background: Long-term treatment of schizophrenia with antipsychotics is crucial for relapse prevention, but a prolonged blockade of D(2) dopamine receptors may lead to the development of supersensitivity psychosis. We investigated the chronic effects of aripiprazole (ARI) on dopamine sensitivity. Me...

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Detalles Bibliográficos
Autores principales: Tadokoro, Shigenori, Okamura, Naoe, Sekine, Yoshimoto, Kanahara, Nobuhisa, Hashimoto, Kenji, Iyo, Masaomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446226/
https://www.ncbi.nlm.nih.gov/pubmed/21402722
http://dx.doi.org/10.1093/schbul/sbr006