LARGE enzyme activity deciphered: a new therapeutic target for muscular dystrophies

A significant proportion of severe, inherited congenital muscular dystrophies are due to aberrant glycosylation of the extracellular matrix receptor α-dystroglycan and a consequent lack of ligand-binding activity. A key member of this glycosylation pathway is the LARGE protein, which was originally...

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Detalles Bibliográficos
Autor principal: Hewitt, Jane E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Highlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446273/
https://www.ncbi.nlm.nih.gov/pubmed/22458537
http://dx.doi.org/10.1186/gm322

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446273/
https://www.ncbi.nlm.nih.gov/pubmed/22458537
http://dx.doi.org/10.1186/gm322

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