Epigenetic variability in cells of normal cytology is associated with the risk of future morphological transformation

BACKGROUND: Recently, it has been proposed that epigenetic variation may contribute to the risk of complex genetic diseases like cancer. We aimed to demonstrate that epigenetic changes in normal cells, collected years in advance of the first signs of morphological transformation, can predict the ris...

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Detalles Bibliográficos
Autores principales: Teschendorff, Andrew E, Jones, Allison, Fiegl, Heidi, Sargent, Alexandra, Zhuang, Joanna J, Kitchener, Henry C, Widschwendter, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446274/
https://www.ncbi.nlm.nih.gov/pubmed/22453031
http://dx.doi.org/10.1186/gm323

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446274/
https://www.ncbi.nlm.nih.gov/pubmed/22453031
http://dx.doi.org/10.1186/gm323

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