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Epigenetic variability in cells of normal cytology is associated with the risk of future morphological transformation
BACKGROUND: Recently, it has been proposed that epigenetic variation may contribute to the risk of complex genetic diseases like cancer. We aimed to demonstrate that epigenetic changes in normal cells, collected years in advance of the first signs of morphological transformation, can predict the ris...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446274/ https://www.ncbi.nlm.nih.gov/pubmed/22453031 http://dx.doi.org/10.1186/gm323 |